Fermenter_Stirred Tank Bioreactor_StirCradle TM

Analytical Equipment

VacciXcell completes its bioprocessing solutions by providing a system for the fermentation of microorganisms and culture of suspension cells – StirCradle™ and StirCradle™-Pro. The StirCradle is the laboratory-scale autoclable system while the StirCradle-Pro is the SIP pilot/production scale system.

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Full Description

VacciXcell offers a wide range of fermenter sizes, starting from 5L laboratory scale all the way to 2000L production scale.

StirCradle™

StirCradle is a desk-type bioreactor/fermenter for microorganism culture. By combining the vessel, workbench, controller and peristaltic pumps into one integrated system, this patented system effectively provides the most capacity for a small footprint. The StirCradle is ideal for research and development involving microorganism or animal and plant cell cultures.

The StirCradle-Pro is a fully stainless steel fermenter/bioreactor system designed with an automated 5-step cycle SIP system for both culture medium and reactor vessel. VacciXcell offers a wide range of standard reactor capacities from 20L up to 1000L; however, customized reactor sizes are available should the users require

Features :

The patented design of the mixing system optimizes DO control during high density culturing
Can be used with oxygen enrichment devices and/or multiple gas devices to achieve ideal gas mix for cell culture
Vessel can be easily changed to suit different applications
Light weight and small footprint vs similar competitor models
Patented chassis thermal loop interchange design to provide the best temperature control
Four (4) built-in peristaltic pumps (with option to add up to 3 more) with assignable functions.
Two integrated USB port for ease of saving online data to external memory eliminating the need for a dedicated PC.
Datalog can record for up to 25 days with one (1) or two (2) minute/s intervals for all parameters.
8”TFT Full ColorTouch Screen for Human-Machine Interface with easily replaceable panel membrane
Able to save up to 20 customized culture settings (with 50 culture conditions each)
Equipped with an easy-to-detach stainless steel condenser for easy cleaning
Can connect to downstream processing equipment to obtain high concentration of desired product
Exhaust gas analyzer can be connected to the internet for online monitoring
Free remote monitoring App viewable in smartphones, tablets, laptops or PCs (static IP address required)

Applications

Research and Development
Biopharmaceuticals
Proteomics
Laboratory-scale productions

Parameters

Temperature control
Anti-foam conditions
Speed control
Feed conditions
pH control
DO control
Air control

Models

Model	StirCradle 5L	StirCradle 7.5L	StirCradle 10L
Nominal Volume	5.0L	7.5L	10.0L
Working Volume	1.3 ~ 4.0L	2 ~ 6.0L	2.5 ~ 8.0L
Tank N.W.	9 kg	10.5 kg	11.5 kg
Maximum Height (Consider Placing Autoclave)	460 mm (with condenser)	640 mm (with condenser)	570 mm (with condenser)
Maximum Outer Diameter	196 mm	220 mm	245 mm
Agitation	Drive	AC servo drive with automatic feedback system able to compensate for speed and torque
Range	1 ~ 1200 rpm (adjustable in increments of 1rpm)
Sensor	Optical coupler
Control	PID human-machine touch panel control
Mixing blades	Includes two sets of Turbine six-blade type mixing blade and one set of whipped wing. Other Impellers are optional
Display	Touch screen HMI dynamic display
Oxygen Transfer Rate	350 mM O2/L/Hr or higher
Temperature	Range	Cooling water +5 ? to 80 ° C ± 0.1 ° C, or when using an external cooling system +4 ? to 80 ° C. ± 0.1 ° C, rapid temperature changes 1 ? / min (25 ~ 45 ?)
Sensor	PT 100Ω
Control	PID human-machine touch panel control with automatic over-temperature protection
Ventilation	Flow Adjustment System	Mass flow meter. A reserved second gas port is available for additional gases such as oxygen, nitrogen, ammonia and other special gases
Air Flow	0~10.00 nL/min
Ventilation	Quick release air sparging to minimize the bubbles and effectively increase the OTR value
Filter	0.2μm PTFE Millipore
Exhaust System	Filter	0.2μm PTFE Millipore
Condensation	Stainless steel water-cooled condenser can be easily disassembled
pH	Set / Display Range	0~14.00 ±0.01
Control Mode	PID human-machine touch panel control. Gas or liquid can be selected as agent (ex, ammonia or liquid ammonia).
Electrode	Mettler Toledo / Ingold Type or Hamilton Type
DO	Setting Range	0~100.0% ±0.1
Display Range	0~200.0% ±0.1
Control Mode	PID human-machine touch panel control with programmable commands
Electrode	Mettler Toledo / Ingold Type or Hamilton Type (Can be shared)
Pump	Control	Manual or automatic control with adjustable speed. Can be installed with five different sizes of silicon tubes (0.5mm, 0.8mm, 1.2mm, 3.6mm, and 4.8mm diameter).
Display	0 to 100% speed adjustable, flow control
The Overall Size of	Wide	560mm
Depth	600mm
High	380mm
Power Supply	220VAC single-phase
Display Screen	8 "industrial grade touch panel. TFT LCD. 65,535 colored
Interface	Compatible RS232C standard communication interface for PC link control (Remote control), can also be changed into RS422 or RS485
Record Output	2 USB ports for saving data into external memory